Research Article

Lovastatin Production by Aspergillus terreus Using Agro-Biomass as Substrate in Solid State Fermentation

Table 1

Effect of nitrogen source and mineral solution on lovastatin production in solid state fermentation by A. terreus using rice straw (RS) and oil palm frond (OPF) as substrates.

TreatmentsLovastatin production (mg/kg DM)
ATCC 20542ATCC 74135

RS 1 5 4 . 4 8 ± 2 2 . 8 8 a 1 5 7 . 0 7 ± 1 . 9 2
RS plus mineral 1 1 9 . 3 5 ± 1 6 . 5 9 a b 1 4 6 . 0 9 ± 7 . 4 9
RS plus mineral and urea 9 6 . 3 ± 3 . 0 2 b c 1 1 8 . 2 6 ± 6 . 3 8
RS plus mineral and soybean meal 1 2 6 . 3 6 ± 2 2 . 8 4 a b 1 3 9 . 6 3 ± 2 5 . 4 5
RS plus mineral and ammonium sulphate 6 6 . 1 9 ± 3 . 3 9 c 1 2 9 . 3 9 ± 2 1 . 9 0
Significant**NS

OPF 7 . 8 4 ± 0 . 1 4 b 1 3 . 0 9 ± 2 . 2 2 b
OPF plus mineral 9 . 6 6 ± 0 . 0 3 b 7 . 2 ± 1 . 5 5 b
OPF plus mineral and urea 2 1 . 2 5 ± 4 . 6 6 b 1 7 . 5 8 ± 3 . 0 3 b
OPF plus mineral and soybean meal 7 0 . 1 7 ± 4 . 8 4 a 6 3 . 7 6 ± 1 4 . 0 0 a
OPF plus mineral and ammonium sulphate 1 0 . 0 6 ± 0 . 3 1 b 1 1 . 1 6 ± 3 . 4 1 b
Significant****

NS: not significantly different.
**Significantly different at 1% level.
a,b,c indicating that means for each substrate within column are significantly different.