Research Article

Association of Polymorphisms in Mitofusin-2 Gene with Type 2 Diabetes in Han Chinese

Table 4

Common haplotypes in the MFN2 gene.

HaplotypeT2D (%)Control (%) 𝑃 OR (95% CI)

A-C-G-T-C347.95 ( 31.9)474.88 (37.7)0.0070.79 (0.66–0.94)
G-C-C-C-C66.82 (6.1)100.87 (8.0)0.100.76 (0.55–1.05)
G-C-C-T-C35.18 (3.2)40.09 (3.2)0.901.03 (0.65–1.63)
G-C-G-T-G114.87 (10.5)111.74 (8.9)0.141.23 (0.94–1.62)
G-T-C-T-C443.08 (40.6)454.77 (36.2)0.0091.26 (1.06–1.49)
others84.1 (7.7)75.65 (6.0)

Total1092 (100%)1258 (100%)

Haplotype analysis was conducted with rs873458, rs2878677, rs2236058, rs3766742, rs3766741. 𝑃 had no adjustment.