Usefulness of FDG, MET and FLT-PET Studies for the Management of Human Gliomas
Figure 4
A 31-year-old woman with high intensity in the right frontal lobe in FLAIR MRI (a) and slightly enhanced lesion in Gd-enhanced MRI (b). FDG-PET demonstrated increased FDG uptake within the tumor (c). MET-PET demonstrated increased MET uptake within the tumor (d). FLT-PET demonstrated increased FLT uptake within the tumor (e). Areas of different enhancement and uptake between FDG, MET, and FLT are projected on the tumor, in order to perform histological sampling for further correlation during the resection (yellow arrow, red arrow). Yellow arrow demonstrates anaplastic astrocytoma (f) within ratio of FDG-PET (2.85), MET-PET (4.57), and FLT-PET (9.65). Ki-67 index from the specimen indicated by yellow arrow was 20% (g). Red arrow demonstrates diffuse astrocytoma area (h) within ratio of FDG-PET (0.76), MET-PET (2.08), and FLT-PET (4.65). Ki-67 index from the specimen indicated by red arrow was 8% (i).
