Research Article
Usefulness of FDG, MET and FLT-PET Studies for the Management of Human Gliomas
Table 1
Patient characteristics and semiquantitative PET results for FDG, MET, and FLT. Dig: histological diagnosis, DA: diffuse astrocytoma, OA: oligoastrocytoma, O: oligodendroglioma, AA: anaplastic astrocytoma, AOA: anaplastic oligoastrocytoma, AO: anaplastic oligodendroglioma, GBM: glioblastoma multiforme, GS: gliosarcoma, SUV max maximum standardized uptake value, T/N ratio tumor-to-normal tissue count density.
| Case | Age | Sex | Dig. | Ki-67 (%) | FDG SUV max | FDG | MET SUV max | MET | FLT SUV max | FLT |
| 1 | 49 | f | DA | 1.75 | 4.12 | 0.403526 | 2.93 | 1.7757576 | 0.13 | 1.1818182 | 2 | 42 | f | OA | 7.5 | 4.4 | 0.5231867 | 4.37 | 2.5406977 | 0.24 | 1.8461538 | 3 | 52 | f | DA | 1 | 4.96 | 0.5025329 | 3.34 | 1.9306358 | 0.55 | 3.6666667 | 4 | 71 | m | DA | 4 | 3.85 | 0.6514382 | 5.28 | 4.3278689 | 0.76 | 5.4285714 | 5 | 30 | m | DA | 2.5 | 5.65 | 0.495614 | 1.69 | 1 | 0.28 | 1 | 6 | 35 | f | DA | 2.5 | 5.78 | 0.5254545 | 1.57 | 1 | 0.23 | 1 | 7 | 30 | f | DA | 5 | 5.89 | 0.356 | 1.49 | 1.18254 | 0.18 | 1 | 8 | 27 | f | O | 2.3 | 5.34 | 0.8215385 | 1.38 | 1.5164835 | 0.18 | 1.125 | 9 | 49 | f | DA | 5 | 2.71 | 0.5441767 | 1.7 | 1.1971831 | 0.22 | 1.047619 | 10 | 38 | f | DA | 5 | 6.07 | 0.497133 | 2.55 | 1.795775 | 0.28 | 1.75 | 11 | 37 | m | DA | 1 | 23.87 | 2.69 | 4.97 | 2.99 | 0.79 | 2.72 | 12 | 36 | m | OA | 7.7 | 8.01 | 1.055336 | 5.26 | 3.094118 | 0.48 | 2.181818 | 13 | 34 | f | AA | 5 | 6.67 | 0.6778455 | 3.22 | 2.2517483 | 1.15 | 6.7647059 | 14 | 58 | m | AA | 12.5 | 4.46 | 0.566709 | 3.55 | 2.9583333 | 0.28 | 1.8666667 | 15 | 77 | f | AA | 35 | 6.98 | 1.8082902 | 5.07 | 3.5454545 | 0.9 | 5 | 16 | 26 | m | AA | 5 | 4.72 | 0.5777234 | 3.32 | 2.862069 | 0.32 | 2.6666667 | 17 | 66 | f | AOA | 5 | 3.97 | 0.5321716 | 2.93 | 2.4016393 | 0.58 | 3.0526316 | 18 | 60 | f | AA | 10 | 7.59 | 1.1587786 | 3.41 | 2.544776 | 0.94 | 3.91667 | 19 | 36 | f | AA | 6 | 4.27 | 0.5488432 | 4.81 | 2.829412 | 0.37 | 2.176471 | 20 | 43 | f | AA | 30 | 4.74 | 0.629482 | 8.04 | 4.345946 | 0.84 | 2.470588 | 21 | 71 | m | AOA | 50 | 24.02 | 3.1605263 | 5.17 | 4.3445378 | 1.45 | 6.3043478 | 22 | 64 | m | AO | 50 | 8.74 | 1.208852 | 8.18 | 6.544 | 2.51 | 9.653846 | 23 | 28 | f | AOA | 5 | 13.5 | 1.674938 | 9.02 | 5.401198 | 0.98 | 2.227273 | 24 | 79 | f | AA | 5 | 47.57 | 5.3032329 | 5.96 | 3.8701299 | 0.77 | 5.1333333 | 25 | 66 | f | AA | 12.5 | 6.23 | 0.7634803 | 2.61 | 1.482955 | 0.66 | 2.357143 | 26 | 31 | f | AA | 20 | 23.05 | 2.845679 | 6.49 | 4.570423 | 1.64 | 9.647059 | 27 | 45 | m | AA | 7.5 | 14.8 | 1.9865772 | 6.61 | 5.1640625 | 1.06 | 3.2121212 | 28 | 51 | m | GBM | 25 | 14.86 | 2.006192 | 20.88 | 5.7246377 | 11.18 | 6.0812183 | 29 | 22 | f | GBM | 40 | 12.69 | 1.4859485 | 5.21 | 3.196319 | 3.05 | 11.296296 | 30 | 62 | m | GBM | 35 | 7.65 | 0.9634761 | 4.55 | 3.64 | 1.19 | 7 | 31 | 70 | f | GBM | 35 | 5.04 | 0.6990291 | 3.44 | 2.3401361 | 1.37 | 6.2272727 | 32 | 81 | f | GBM | 50 | 13.05 | 2.8935698 | 5.69 | 3.6012658 | 3.74 | 15.583333 | 33 | 55 | f | GBM | 35 | 8.99 | 2.5759312 | 5.35 | 3.4294872 | 2.61 | 3.1829268 | 34 | 29 | f | GBM | 50 | 5.5 | 0.607064 | 3.57 | 1.9944134 | 1.66 | 8.7368421 | 35 | 77 | f | GBM | 45 | 4.6 | 1.281337 | 5.51 | 3.3393939 | 2.15 | 8.9583333 | 36 | 79 | m | GBM | 65 | 9.71 | 2.0442105 | 4.3 | 3.5833333 | 3.68 | 17.52381 | 37 | 69 | f | GBM | 15 | 15.1 | 2.2913505 | 4.98 | 3.254902 | 4.41 | 23.210526 | 38 | 86 | f | GBM | 30 | 10.96 | 1.7734627 | 5.91 | 5.472222 | 2.69 | 15.82353 | 39 | 27 | f | GBM | 30 | 6.51 | 1.4563758 | 3.83 | 2.992188 | 1.53 | 6.652174 | 40 | 61 | m | GBM | 10 | 6.07 | 1.0049669 | 3.68 | 3.2857143 | 1.96 | 7.5384615 | 41 | 53 | m | GBM | 25 | 6.61 | 1.0200617 | 3.31 | 3.412371 | 1.7 | 8.5 | 42 | 62 | m | GBM | 70 | 4.86 | 0.9382239 | 4.54 | 4.09009 | 1.67 | 15.18182 | 43 | 67 | m | GBM | 30 | 5.8 | 0.9148265 | 2.82 | 2.014286 | 1.45 | 9.0625 | 44 | 60 | m | GBM | 40 | 5.97 | 0.894615 | 2.9 | 2.788462 | 1.28 | 7.111111 | 45 | 54 | m | GS | 40 | 6.95 | 0.8742138 | 3.75 | 2.218935 | 2.9 | 12.6087 | 46 | 72 | m | GBM | 50 | 5.55 | 0.9771127 | 3.22 | 2.439394 | 2.28 | 16.28571 | 47 | 68 | f | GBM | 60 | 5.94 | 1.1020408 | 4.08 | 2.4 | 2.99 | 17.58824 | 48 | 53 | f | GBM | 20 | 4.76 | 0.6979472 | 2.63 | 1.992424 | 1.04 | 6.1176471 | 49 | 61 | f | GBM | 70 | 12.2 | 1.75 | 5.64 | 5.271028 | 1.58 | 5.8518519 | 50 | 37 | m | GBM | 20 | 10.31 | 1.19 | 14.08 | 9.7777778 | 1.73 | 6.1785714 | 51 | 33 | m | GBM | 70 | 20.16 | 2.011976 | 8.71 | 4.608466 | 2.85 | 8.6363636 | 52 | 41 | f | GBM | 20 | 24.76 | 3.4057771 | 7.04 | 5.1764706 | 2.22 | 17.076923 | 53 | 26 | m | GBM | 80 | 13.32 | 1.5857143 | 5.43 | 3.878571 | 2.59 | 4.177419 | 54 | 69 | m | GBM | 90 | 27.09 | 5.0166667 | 8.86 | 7.5726496 | 5.44 | 34 |
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