Research Article
Efficacy of Continuously Administered PEDF-Derived Synthetic Peptides against Osteosarcoma Growth and Metastasis
Table 1
Tumour per cent necrosis and apoptosis as determined on haematoxylin and eosin-stained and TUNEL-stained sections of orthotopic tumour, respectively.
| | Water | StVOrth-2 50 μg/kg/day | StVOrth-2 500 μg/kg/day | StVOrth-3 50 μg/kg/day | StVOrth-3 500 μg/kg/day |
| % Necrosis | 28.2% | 31.3% | 8.9% | 46.6% | 33.5% | (±8.01 SEM) | (±11.85 SEM) | (±2.952 SEM) | (±10.04 SEM) | (±4.071 SEM) | % Apoptosis | 20.2% | 15.9% | 3.6% | 39.4% | 41.3% | (±2.22 SEM) | (±1.87 SEM) | (±0.56 SEM) | (±13.89 SEM) | (±10.12 SEM) |
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