Research Article

Molecular Imaging of Mesothelioma with 9 9 m T c -ECG and 6 8 G a -ECG

Table 2

Biodistribution of  99mTc-ECG in mesothelioma-bearing rats.

Percentage of injected dose per gram of tissue weight ( 𝑛 = 3 /time, interval, iv)1
30 min2 h4 h

Blood 0 . 9 8 ± 0 . 0 6 0 . 2 3 ± 0 . 0 3 0 . 1 6 ± 0 . 0 1
Heart 0 . 2 8 ± 0 . 0 2 0 . 0 6 ± 0 . 0 1 0 . 0 4 ± 0 . 0 0
Lung 0 . 6 5 ± 0 . 0 3 0 . 1 6 ± 0 . 0 3 0 . 1 0 ± 0 . 0 0
Thyroid 0 . 5 5 ± 0 . 0 4 0 . 1 2 ± 0 . 0 2 0 . 0 8 ± 0 . 0 0
Pancreas 0 . 2 1 ± 0 . 0 2 0 . 0 5 ± 0 . 0 1 0 . 0 4 ± 0 . 0 1
Liver 1 . 0 5 ± 0 . 0 2 0 . 8 6 ± 0 . 0 7 0 . 5 1 ± 0 . 0 2
Spleen 0 . 5 9 ± 0 . 0 5 0 . 6 1 ± 0 . 0 7 0 . 7 0 ± 0 . 0 2
Kidney 3 . 7 9 ± 0 . 5 7 2 . 0 2 ± 0 . 4 9 1 . 3 3 ± 0 . 1 0
Stomach 0 . 3 5 ± 0 . 0 3 0 . 0 7 ± 0 . 0 1 0 . 0 3 ± 0 . 0 0
Intestine 0 . 2 8 ± 0 . 0 2 0 . 1 1 ± 0 . 0 4 0 . 0 4 ± 0 . 0 1
Uterus 0 . 5 5 ± 0 . 0 4 0 . 1 5 ± 0 . 0 6 0 . 0 8 ± 0 . 0 1
Tumor 0 . 4 7 ± 0 . 0 6 0 . 1 2 ± 0 . 0 1 0 . 0 8 ± 0 . 0 0
Muscle 0 . 1 3 ± 0 . 0 1 0 . 0 3 ± 0 . 0 1 0 . 0 2 ± 0 . 0 0
Bone 0 . 1 6 ± 0 . 0 6 0 . 0 5 ± 0 . 0 1 0 . 0 3 ± 0 . 0 0
Brain 0 . 0 4 ± 0 . 0 0 0 . 0 1 ± 0 . 0 0 0 . 0 1 ± 0 . 0 0
Tumor/blood 0 . 4 7 ± 0 . 0 3 0 . 5 0 ± 0 . 0 3 0 . 5 1 ± 0 . 0 0
Tumor/muscle 3 . 4 9 ± 0 . 2 4 3 . 7 5 ± 0 . 4 4 5 . 0 6 ± 0 . 2 5
Tumor/brain 1 0 . 7 9 ± 0 . 5 0 1 0 . 2 2 ± 1 . 3 7 1 5 . 5 2 ± 0 . 8 9
Uterus/muscle 4 . 1 8 ± 0 . 2 3 4 . 4 9 ± 0 . 9 6 4 . 7 4 ± 0 . 1 6
Tumor/lung 0 . 7 1 ± 0 . 0 7 0 . 7 5 ± 0 . 1 0 0 . 8 5 ± 0 . 0 4

1Values represent the mean ± standard deviation of data from 3 animals.