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Figure 6: Representation of different channels responsible for Ca2+ influx/efflux in mitochondria and the possible interaction of MeHg with these channels. VDAC: outer membrane voltage-dependent anion channel; RAM: rapid uptake model; MCU: inner membrane calcium uniporter channel; mRyR: mitochondrial ryanodine receptor; Ca2+/H+ antiporter; Na+/Ca2+ exchanger; MPTP: mitochondrial permeability transition pore. The scale of structures represented in this scheme does not represent the real size.