Exposure to Low Dose of Cinnabar (a Naturally Occurring Mercuric Sulfide (HgS)) Caused Neurotoxicological Effects in Offspring Mice

Table 1

Hg contents of dam’s blood and offspring (whole body at PND 1) mice after administration with low dose of cinnabar.

Dam’s (whole blood)		Offspring (whole body)	Generation
F0 (Distilled water)	2.0±0.3	1.8±0.1	F1-control
F0 (Cinnabar-10mg/kg/day)	8.1±1.2^*	6.3±0.5^*	F1-Cinnabar
F1 (Cinnabar-10mg/kg/day)^*	6.3±0.4	𝟓.2±0.2^*	F2-Cinnabar

At postnatal day 1 (PND 1), the offspring mice (pups) were randomly selected as representatives of their respective litters (four or five per litter). Hg content was expressed as ng/g of wet-weight and presented as mean ± SE.
^∗𝑃<0.05 as compared with control group.