Research Article

All-trans-Retinoic Acid Ameliorated High Fat Diet-Induced Atherosclerosis in Rabbits by Inhibiting Platelet Activation and Inflammation

Figure 3

Platelet CD62-P expressions in different groups. Isolated platelets were incubated with FITC-labelled anti-CD62P antibody, and surface CD62-P changes were monitored by flow cytometry. Representative histograms from every group are shown. (a) The expression of CD62-P on the resting platelets surface from different groups. (b) The expression of CD62-P on the thrombin-activated platelets from different groups. (c) The expression of CD62-P on the ADP-activated platelets from different groups. (d) Mean fluorescence intensity (MFI) of CD62-P expression on platelets surface in different groups. Data are mean ± standard deviation (SD). Comparisons between groups were carried out using one-way analysis of variance (ANOVA) and Student-Newman-Keuls (SNK) method ( 𝑛 = 6 ). ** 𝑃 < 0 . 0 1 compared to control group, 𝑃 < 0 . 0 5 , ▲▲ 𝑃 < 0 . 0 1 compared to HFD group.
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