Research Article

All-trans-Retinoic Acid Ameliorated High Fat Diet-Induced Atherosclerosis in Rabbits by Inhibiting Platelet Activation and Inflammation

Table 2

Levels of fibrinogen and cytokines in different groups.

GroupFibrinogen (g/L)TNF-α (pg/mL)IL-6 (pg/mL)

Control 2 . 4 2 ± 0 . 2 9 7 9 . 5 4 ± 1 2 . 5 3 3 8 . 7 6 ± 6 . 3 6
HFD 4 . 0 3 ± 0 . 3 6 * 1 4 2 . 1 2 ± 1 4 . 5 7 * 6 2 . 0 4 ± 6 . 3 9 *
Rosuvastatin 3 . 6 9 ± 0 . 2 4 1 0 1 . 8 8 ± 1 6 . 7 8 4 9 . 9 7 ± 7 . 3 2
atRA 2 . 8 7 ± 0 . 3 0 9 5 ± 1 1 . 8 9 4 3 . 8 2 ± 5 . 7 1

* 𝑃 < 0 . 0 5 compared to control group; 𝑃 < 0 . 0 5 compared to HFD group.