In Vivo Clearance of Alpha-1 Acid Glycoprotein Is Influenced by the Extent of Its N-Linked Glycosylation and by Its Interaction with the Vessel Wall
Figure 5
The disappearance of injected AGP from the plasma of mice following intravenous injection is altered by systemic hyaluronidase treatment. Radioiodinated AGP was injected into mice with (AGP + hy’ase) or without (AGP) concurrent hyaluronidase treatment, and acid-precipitable radioactivity, shown as the percentage of the dose remaining in plasma, was followed over time, .