Table 1: Variables used for the training of the LVQ NN classifier.

Variable nameVariable descriptionVariable value range

Cytological diagnosisThe result of the cytological examination expressed according to bethesda system6: SCC or ADENOCA,
5: HSIL, 4: ASC-H, 3: LSIL, 2: ASCUS, 1: WNL
Binary HPV testThe result of the HPV DNA test Has a value of 0 if no HPV subtype was found and 1 if there was found even a single subtype
A6, A11, A16, A18, A26, A31,
A33, A35, A39, A40, A42, A43,
A44, A45, A51, A52, A53, A54, A56, A58, A59, A61, A62, A66, A68, A70, A71, A72, A73,
A81, A82, A83, A84, A85, A89
The existence of individual subtypes according to the HPV typing examination For each individual subtype: 1 if it was found and 0 if it was not found
Number of HPV subtypesThe number of HPV subtypes found by the HPV DNA testExpressed as number of identified subtypes
High-risk HPV subtypesThe number of high risk and very high risk subtypes found by the HPV DNA testExpressed as number of identified high risk or very high risk subtypes
N16The result of the E6/E7 mRNA test for HPV subtype 160 if negative and 1 if positive
N18The result of the E6/E7 mRNA test for HPV subtype 180 if negative and 1 if positive
N31The result of the E6/E7 mRNA test for HPV subtype 310 if negative and 1 if positive
N33The result of the E6/E7 mRNA test for HPV subtype 330 if negative and 1 if positive
Flow test resultThe result of the identification of E6/E7 mRNA expression of high risk HPV using FLOW cytometry technique0 if negative (positive expression <1.5%) and 1 if positive (positive expression >1.5
p16 resultThe result of the P16 immunocytochemical examination0 if negative and 1 if positive
Histological examinationThe outcome of the histological examination1 for positive or 0 for negative