A Standardized Extract of Ginkgo biloba Neutralizes Cisplatin-Mediated Reproductive Toxicity in Rats

Figure 4

Immunohistochemical staining showing COX-2 expression in control (N), GB alone (GB), CIS alone (CIS), and the three GB-protected rats (CIS+L: 50 mg/kg GB; CIS+M: 100 mg/kg GB; CIS+H: 200 mg/kg GB). Photomicrographs show variable levels of COX-2 expression in different experimental groups. Brown staining indicates COX-2 expression. CIS group show increased levels of COX-2 expression compared to N and all three GB-protected groups. Tissues were counterstained with hematoxylin, 400x.