Frequency of TLR 2, 4, and 9 Gene Polymorphisms in Chinese Population and Their Susceptibility to Type 2 Diabetes and Coronary Artery Disease

Table 3

Genotype distribution of TLR9-1486T/C promoter polymorphism.

SNP	Genotypes			Total	Allele frequency
	TT	TC	CC		C	T
Non-CAD	46	41	12	99	65 (32.8%)	133 (67.2%)
CAD	135	147	51	333	249 (37.4%)	417 (62.6%)
P		𝜒^2=1.304𝑃=0.521			𝜒^2=1.371 𝑃=0.242
Non-DM	91	103	34	239	171 (37.5%)	285 (62.5%)
DM	79	85	29	193	143 (37%)	243 (63%)
P		𝜒^2=0.058𝑃=0.971			𝜒^2=0.018 𝑃=0.892
Control	23	37	6	66	49 (37.1%)	83 (62.9%)
CAD	69	76	28	173	132 (38.2%)	214 (61.8%)
DM	13	14	6	33	26 (39.4%)	40 (60.6%)
DM + CAD	66	71	23	160	117 (36.6%)	203 (63.4)
P	𝜒^2=4.258𝑃=0.642				𝜒^2=0.292𝑃=0.962

Control: control group; CHD: CAD group; DM: T2DM group; DM + CAD = type 2 diabetes mellitus plus coronary artery disease group.