Research Article

Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

Figure 1

Classification of the comets. Normal nucleus (class 0), halo around the nucleus (class 1), and gradual increase in the length of the comet tail, evolving in parallel with a decrease in the nuclear DNA content (class 2 and class 3). Alkaline comet assay reflecting global DNA damage (ssb + dsb) (upper panel), and neutral comet assay reflecting dsb mainly (lower panel).
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