Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

Table 2

Distribution of percentage of DNA damage evaluated in alkaline comet assay (ssb + dsb) in control, LG-SIL, and HG-SIL women.

		Alkaline comet assay (ssb + dsb)
Group	𝑁	Class 0	Class 1	Class 2	Class 3	Total
Control	10	70 (0)	9 (9)	9 (18)	12 (36)	100 (63)
LG-SIL	10	58 (0)	9 (9)	10 (20)	23 (69)	100 (98)
HG-SIL	10	42 (0)	9 (9)	17 (34)	32 (96)	100 (139)

The values in parenthesis are “arbitrary units” obtained by the multiplication of the number of cells by each score (0–3). Pearson correlation coefficient (𝑟²=0.99, 𝑃=0.03).