Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

Table 4

DNA damage (ssb + dsb) and dsb evaluated by DBD-FISH on neutral comet in women with LG-SIL, HG-SIL and in control women.

	DBD-FISH on neutral comet
	Control; (mean ± SD)	LSIL; (mean ± SD)	HSIL; (mean ± SD)
Migration length (dsb)a	6.37±3.11	8.41±7.31	18.75±6.47 *
Fluorescence intensity (ssb)b	67^E3±42^E3	256^E3±172^E3	731^E3±275^E3∗

aMigration length is defined as the distance between the center of the comet head and the end of the tail (𝜇m). bAverage pixel grey. *ANOVA test; Different to control 𝑃<0.05.