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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 386230, 4 pages
http://dx.doi.org/10.1155/2012/386230
Research Article

The Difference in Pharmacokinetics and Pharmacodynamics between Extended-Release Fluvastatin and Immediate-Release Fluvastatin in Healthy Chinese Subjects

Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai 200032, China

Received 7 February 2012; Revised 28 April 2012; Accepted 14 May 2012

Academic Editor: Kazim Husain

Copyright © 2012 H. R. Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Bruckert, M. P. Verpilleux, S. Dejager, and J. Isaacsohn, “Comparison of efficacy and safety assessment of Fluvastatin in patients <65 years versus ≥65 years of age,” American Journal of Cardiology, vol. 96, no. 8, pp. 1142–1148, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. V. L. Lanchote, A. Rocha, F. U. de Albuquerque, E. Barbosa Coelho, and P. S. Bonato, “Stereoselective analysis of fluvastatin in human plasma for pharmacokinetic studies,” Journal of Chromatography B, vol. 765, no. 1, pp. 81–88, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Ostadal, D. Alan, J. Vejvoda et al., “Immediate effect of fluvastatin on lipid levels in acute coronary syndrome,” Molecular and Cellular Biochemistry, vol. 306, no. 1-2, pp. 19–23, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. C. D. Scripture and J. A. Pieper, “Clinical pharmacokinetics of fluvastatin,” Clinical Pharmacokinetics, vol. 40, no. 4, pp. 263–281, 2001. View at Scopus
  5. J. L. Isaacsohn, J. LaSalle, G. Chao, and L. Gonasun, “Comparison of treatment with fluvastatin extended-release 80-mg tablets and immediate-release 40-mg capsules in patients with primary hypercholesterolemia,” Clinical Therapeutics, vol. 25, no. 3, pp. 904–918, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. D. Barilla, P. Prasad, M. Hubert, and K. Gumbhir-Shah, “Steady-state pharmacokinetics of fluvastatin in healthy subjects following a new extended release fluvastatin tablet, lescol XL,” Biopharmaceutics and Drug Disposition, vol. 25, no. 2, pp. 51–59, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. C. M. Battantyne, F. Pazzucconi, X. Pintó et al., “Efficacy and tolerability of fluvastatin extended-release delivery system: a pooled analysis,” Clinical Therapeutics, vol. 23, no. 2, pp. 177–192, 2001. View at Publisher · View at Google Scholar · View at Scopus