About this Journal Submit a Manuscript Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 398398, 6 pages
http://dx.doi.org/10.1155/2012/398398
Research Article

Expression and Localization of Ryanodine Receptors in the Frog Semicircular Canal

1Department of Physiology, Section of General Physiology, University of Pavia, 27100 Pavia, Italy
2Brain Connectivity Center, IRCCS Foundation National Neurological Institute C. Mondino, 27100 Pavia, Italy
3Department of Physiology, Section of Human Physiology, University of Pavia, 27100 Pavia, Italy

Received 1 July 2011; Revised 5 October 2011; Accepted 11 October 2011

Academic Editor: Vickram Ramkumar

Copyright © 2012 Paola Perin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Mammano, M. Bortolozzi, S. Ortolano, and F. Anselmi, “Ca2+ signaling in the inner ear,” Physiology, vol. 22, no. 2, pp. 131–144, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. M. Lioudyno, H. Hiel, J. H. Kong et al., “A “synaptoplasmic cistern” mediates rapid inhibition of cochlear hair cells,” Journal of Neuroscience, vol. 24, no. 49, pp. 11160–11164, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. A. Lelli, P. Perin, M. Martini et al., “Presynaptic calcium stores modulate afferent release in vestibular hair cells,” Journal of Neuroscience, vol. 23, no. 17, pp. 6894–6903, 2003. View at Scopus
  4. M. Beurg, A. Hafidi, L. J. Skinner et al., “Ryanodine receptors and BK channels act as a presynaptic depressor of neurotransmission in cochlear inner hair cells,” European Journal of Neuroscience, vol. 22, no. 5, pp. 1109–1119, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. M. L. Rossi, I. Prigioni, L. Gioglio et al., “IP3 receptor in the hair cells of frog semicircular canal and its possible functional role,” European Journal of Neuroscience, vol. 23, no. 7, pp. 1775–1783, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. M. E. Schnee, J. Santos-Sacchi, M. Castellano-Muñoz, J. H. Kong, and A. Ricci, “Calcium-dependent synaptic vesicle trafficking underlies indefatigable release at the hair cell afferent fiber synapse,” Neuron, vol. 70, no. 2, pp. 326–338, 2011. View at Publisher · View at Google Scholar · View at PubMed
  7. A. W. Hendricson and P. S. Guth, “Transmitter release from Rana pipiens vestibular hair cells via mGluRs: a role for intracellular Ca++ release,” Hearing Research, vol. 172, no. 1-2, pp. 99–109, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Rossi and V. Sorrentino, “Molecular genetics of ryanodine receptors Ca2+-release channels,” Cell Calcium, vol. 32, no. 5-6, pp. 307–319, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Tijskens, G. Meissner, and C. Franzini-Armstrong, “Location of ryanodine and dihydropyridine receptors in frog myocardium,” Biophysical Journal, vol. 84, no. 2, part 1, pp. 1079–1092, 2003. View at Scopus
  10. H. Oyamada, T. Murayama, T. Takagi et al., “Primary structure and distribution of ryanodine-binding protein isoforms of the bullfrog skeletal muscle,” Journal of Biological Chemistry, vol. 269, no. 25, pp. 17206–17214, 1994. View at Scopus
  11. P. Wangemann, “Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential,” Journal of Physiology, vol. 576, no. 1, pp. 11–21, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. U. Laforenza, G. Gastaldi, M. Polimeni et al., “Aquaporin-6 is expressed along the rat gastrointestinal tract and upregulated by feeding in the small intestine,” BMC Physiology, vol. 9, no. 1, article 18, pp. 1–12, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. R. Meccariello, M. F. Franzoni, R. Chianese et al., “Interplay between the endocannabinoid system and GnRH-I in the forebrain of the anuran amphibian Rana esculenta,” Endocrinology, vol. 149, no. 5, pp. 2149–2158, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. U. K. Laemmli, “Cleavage of structural proteins during the assembly of the head of bacteriophage T4,” Nature, vol. 227, no. 5259, pp. 680–685, 1970. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Kashiyama, T. Murayama, E. Suzuki, P. D. Allen, and Y. Ogawa, “Frog α- and β-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line,” PLoS One, vol. 5, no. 7, Article ID e11526, 2010.
  16. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Scopus
  17. J. Zhou, B. S. Launikonis, E. Ríos, and G. Brum, “Regulation of Ca2+ sparks by Ca2+ and Mg2+ in mammalian and amphibian muscle. An RyR isoform-specific role in excitation-contraction coupling?” Journal of General Physiology, vol. 124, no. 4, pp. 409–428, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  18. B. Perry, H. C. Jensen-Smith, R. F. Ludueña, and R. Hallworth, “Selective expression of β tubulin isotypes in gerbil vestibular sensory epithelia and neurons,” Journal of the Association for Research in Otolaryngology, vol. 4, no. 3, pp. 329–338, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  19. P. Cameron, S. Gaboyard, S. D. Price, M. Klapczynski, D. Modi, and A. Lysakowski, “Multiple isoforms of ryanodine and IP3 receptor genes expressed in rat inner ear organs,” Molecular Biology Deafness Hearing, p. 160, 2004.
  20. C. S. Haarmann, A. F. Dulhunty, and D. R. Laver, “Regulation of skeletal ryanodine receptors by dihydropyridine receptor II-III loop C-region peptides: relief of Mg2+ inhibition,” Biochemical Journal, vol. 387, no. 2, pp. 429–436, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  21. T. Murayama and N. Kurebayashi, “Two ryanodine receptor isoforms in nonmammalian vertebrate skeletal muscle: possible roles in excitation-contraction coupling and other processes,” Progress in Biophysics and Molecular Biology, vol. 105, no. 3, pp. 134–144, 2011. View at Scopus
  22. B. W. Edmonds, F. D. Gregory, and F. E. Schweizer, “Evidence that fast exocytosis can be predominantly mediated by vesicles not docked at active zones in frog saccular hair cells,” Journal of Physiology, vol. 560, no. 2, pp. 439–450, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  23. J. H. Lee, T. Chiba, and D. C. Marcus, “P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells,” Journal of Neuroscience, vol. 21, no. 23, pp. 9168–9174, 2001. View at Scopus
  24. P. G. Milhaud, S. R. Pondugula, J. H. Lee et al., “Chloride secretion by semicircular canal duct epithelium is stimulated via β2-adrenergic receptors,” American Journal of Physiology—Cell Physiology, vol. 283, no. 6, pp. C1752–C1760, 2002. View at Scopus