406273.fig.004a
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406273.fig.004b
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Figure 4: The glioblastoma-promoting effect of A2 is p11 independent. (a) When A2 expression in GL261 murine glioma cells was suppressed with siRNA, p11 expression remained intact. (b) Suppression of A2 expression significantly dampened the growth of intracranial gliomas derived from stereotactically implanted cells. Reproduced with permission [49].