417675.fig.001a
(a)
417675.fig.001b
(b)
Figure 1: (a) The results of Western blotting assay for anti-NAPlr antibody titers in patients with acute poststreptococcal glomerulonephritis (APSGN), patients with a streptococcal infection (SI) without renal involvement, pediatric patients without renal disease, and normal healthy adults (see Table 1 for ages of subjects in each group). Values are means ± SEM. * 𝑃 < 0 . 0 5 for APSGN versus SI, pediatrics, and normal adults by t test. (b) ASO titers for the same groups of patients. The titers in the APSGN and SI groups are significantly higher than those in the normal adults and the pediatric patients without renal disease. Values are means ± SEM. ** 𝑃 < 0 . 0 0 1 for APSGN or SI versus those in other groups by t test.