417675.fig.004a
(a)
417675.fig.004b
(b)
Figure 4: (a) Urinary plasmin activity assessed by chromogenic assay and corrected for urinary creatinine concentration. Results are expressed as corrected mean activity ± SE. * 𝑃 < 0 . 0 1 versus normal control; 𝑃 < 0 . 0 1 versus IgAN. (b) Representative casein gel zymography results for a plasmin standard and urine supernatants from normal controls, patients with IgAN, and patients with APSGN. Graph shows mean ± SE of the density of 80-kDa bands in casein gel zymography expressed in arbitrary units. * 𝑃 < 0 . 0 5 versus normal controls.