Table 1: Comparison of the biomarkers of CSC and normal stem cell.

Cancer typeCSC markerNormal stem cellMarkerReferences

Acute myelogenous leukemiaCD34+CD38Mouse embryonic stem cellOct-4[64]
SSEA-1[65]
GliomaNestin, HOXD9Human embryonic stem cellSSEA-3
SSEA-4, Oct-4
[65]
BreastALDH1, TAZ CD44+/CD24/linTRA-1-60
TRA-1-81
[65]
ColonCD166Neural stem cellCD133[66]
ProstateTRA-1-60
CD151, CD 166
Nestin[66]
PancreasESAHepatic stem cellEpCAM[43]
LiverCD90, EpCAM
CD13
Mammary stem cellCD49f+ E p C A M n e g - l o w [67]
Breast, liver, and pancreasALDHALDH1[17, 68]
Glioma, lung, colon, pancreas, and liverCD133
Pancreas, colon, and liverCD24, CD44
Breast, pancreas, and lungABCG2

CD49f: 𝛼 6 integrin; Lin: Lineage surface antigen; SSEA: stage-specific embryonic antigen.