Efficiency of Ferritin as an MRI Reporter Gene in NPC Cells Is Enhanced by Iron Supplementation

Figure 6

MRI of tumors over-expressing FTH1 in vivo. Representative 𝑇₂-wighted images of mice with inoculation of B-7 cells (right) and parent cells (left) were acquired at 21 days postinoculation without (a) or with (b) FAC supplementation in the drinking water. (c) 𝑅₂ at the tumor region. (d) Effects of FTH1 overexpression on the tumor growth. B-7 cells and parent cells were inoculated into the hind flank of nude mice, and tumor volumes were measured from MR images at the indicated time points. Data were expressed as mean ± SD for 6 experiments. (*𝑃<0.05 and ^#𝑃<0.01.)

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