Table 3: Synonymous codon usages of complete coding region of HMPV, human cell, AMPV, and bird cell.

AACodon aRSCU bRSCU cRSCU dRSCU

AlaGCU1.361.081.02 1.42
GCC0.551.60.77 1.33
GCA1.890.921.99 0.98
GCG0.20.440.22 0.27

ArgCGU0.120.480.15 0.00
CGC0.131.080.14 0.55
CGA0.310.660.34 0.27
CGG0.231.20.41 1.09
AGA3.581.262.86 2.18
AGG1.631.262.10 1.91

AsnAAU1.130.941.08 1.41
AAC0.871.060.92 0.59

AspGAU1.260.921.12 0.88
GAC0.741.080.89 1.12

CysUGU1.040.921.11 0.67
UGC0.961.080.89 1.33

GlnCAA1.270.541.19 0.48
CAG0.731.460.81 1.52

GluGAA1.260.841.11 0.75
GAG0.741.160.89 1.25

GlyGGU1.080.640.89 0.43
GGC0.731.360.68 1.19
GGA1.4911.43 1.08
GGG0.7111.01 1.30

HisCAU1.130.841.00 0.35
CAC0.871.161.00 1.65

IleAUU1.21.081.02 1.78
AUC11.410.90 1.03
AUA0.80.511.08 0.19

LeuUUA1.440.481.19 0.42
UUG1.080.781.36 0.85
CUU1.140.780.83 0.56
CUC0.641.20.57 0.99
CUA0.850.420.92 0.28
CUG0.842.41.13 2.89

LysAAA1.210.861.12 0.93
AAG0.791.140.88 1.07

PheUUU1.320.921.27 1.33
UUC0.681.080.73 0.67

ProCCU1.151.161.12 1.22
CCC0.821.280.74 1.22
CCA1.81.121.78 1.47
CCG0.230.440.36 0.08

SerUCU0.971.140.93 0.71
UCC0.631.320.72 1.15
UCA1.460.91.37 1.06
UCG0.130.30.18 0.26
AGU1.460.91.41 0.44
AGC1.361.441.30 2.38

ThrACU1.1710.98 0.16
ACC0.921.440.83 1.28
ACA1.751.121.91 1.76
ACG0.160.440.27 0.80

TyrUAU1.340.881.14 0.95
UAC0.661.120.86 1.05

ValGUU1.460.721.17 0.57
GUC0.730.960.72 0.91
GUA0.930.480.87 0.80
GUG0.881.841.24 1.71

The number in this table is shown as relative synonymous codon usage values (RSCU) and aRSCU values represent values in HMPV, bRSCU values represent values in human host cell, cRSCU values represent values in AMPV, and dRSCU values represent values in bird cell. All preferred codons are shown in bold. AA is abbreviation of amino acid.