Development of Animal Model for Studying Deep Second-Degree Thermal Burns

Table 2

Histopathological analysis on the degree of inflammatory intensity, presence of granulation tissue, and fibrosis in the skin after deep second-degree thermal burn. Samples were obtained on days 7, 14, 21, and 28 after burn wound induction.

Time	Animal	Inflammatory response	Granulation tissue	Fibrosis
7th day	1	+++	+	−
	2	+++	+	−
	3	+++	+	−
14th day	1	+	++	+
	2	++	+++	+
	3	++	+++	+
21st day	1	+	+	+
	2	+	+	++
	3	+	++	++
28th day	1	−	−	++
	2	−	−	++
	3	−	−	++

Intensity of the evaluated parameters was scored as −: absent, +: mild presence, ++: moderate presence; +++: strong presence.