Review Article

Artificial Chromosomes to Explore and to Exploit Biosynthetic Capabilities of Actinomycetes

Table 1

Shuttle E. coli-Streptomyces artificial chromosomes.

VectorDerived fromattP-int cassette derived fromResistance toReference

pPAC-S2pCYPAC2C31Kanamycin/thiostrepton in E. coli/Streptomyces [21]
pSTREPTOBAC VpBACe3.6C31Apramycin in E. coli/Streptomyces [22]
pSBACpCC1BACBT1Apramycin in E. coli/Streptomyces [23]