Asbestos-Induced Cellular and Molecular Alteration of Immunocompetent Cells and Their Relationship with Chronic Inflammation and Carcinogenesis

Figure 3

Schematic model showing mechanisms of asbestos-induced carcinogenesis and genomic/epigenetic changes found in mesothelioma cells, carcinogenic activities of asbestos fibers, and the relationship of the immunological effects of asbestos in regard to chronic inflammation and reduced tumor immunity.