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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 503241, 28 pages
http://dx.doi.org/10.1155/2012/503241
Research Article

The Safety of Cruciferous Plants in Humans: A Systematic Review

1Pediatric Neurosciences, Department of Pediatrics, Stollery Children's Hospital, University of Alberta, Room 3-469, Edmonton Clinic Health Academy (ECHA), 11405-87 Avenue, Edmonton, AB, Canada T6G 1C9
2CARE Program, Department of Pediatrics, University of Alberta, Edmonton Clinic Health Academy (ECHA), 11405-87 Avenue, Edmonton, AB, Canada T6G 1C9
3School of Public Health, University of Alberta, Edmonton Clinic Health Academy (ECHA), 11405-87 Avenue, Edmonton, AB, Canada T6G 1C9

Received 27 July 2011; Accepted 11 October 2011

Academic Editor: Ikhlas A. Khan

Copyright © 2012 Ori Scott et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary material provided includes: (1) Causality Algorithm Used by the Health Product Safety Information Division of the WHO Collaborating Centre for International Drug Monitoring. This algorithm was used in our study to assess the strength of causal relationship between suspected perpetrators (cruciferous plants) and adverse effect reported; (2) A complete list of search strategies. This includes all search strings exactly as entered to the different databases: Medline, Embase, Pascal and IPA (International Pharmaceutical Abstracts); and (3) The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Guideline Checklist. This includes the official set of all required items which must be included and reported in a systematic review. The PRISMA guidelines are endorsed by PROSPERO, the International Prospective Register of Systematic Reviews.

  1. Supplementary Material