The Safety of Cruciferous Plants in Humans: A Systematic Review
Table 1
Eligibility criteria and data extracted1.
PICOS
Eligibility criteria
Data extracted
Patient
All human subjects were included
Age, concurrent medical conditions and treatments, reason for intervention (where relevant)
Intervention
All types of exposure (oral, topical, or respiratory) to cruciferous plants, their derivatives, or their constituents
Plant or substance exposed to, route of exposure, duration of exposure, dose (if available)
Comparators
Reports with or without a comparator group. Reports without control groups were included in order to include all potential adverse events
Numbers in the intervention and comparator groups (when relevant)
Outcome
Reports of presence or absence of adverse events
Presence or absence of adverse events, description of adverse event, acute management of adverse event (for case reports), outcome (when available), and causality
Study design
All study designs which were relevant to the assessment of safety were included. Studies in all languages were included and translated when necessary
Type of study design and setting
1PICOS: patient, intervention, comparators, outcome, study design.