- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 506159, 7 pages
Temporal and Quantitative Analysis of Atherosclerotic Lesions in Diet-Induced Hypercholesterolemic Rabbits
1Research Institute of Atherosclerotic Disease, Xi’an Jiaotong University School of Medicine, Xi'an 710061, China
2Department of Molecular Pathology, University of Yamanashi, Chuo 409-3898, Japan
3Key Laboratory of Environment and Genes Related to Diseases of the Education Ministry, Xi’an Jiaotong University School of Medicine, Shaanxi, Xi'an 710061, China
Received 23 July 2011; Revised 24 November 2011; Accepted 12 December 2011
Academic Editor: George E. Plopper
Copyright © 2012 Qi Yu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- P. Libby and M. Aikawa, “Stabilization of atherosclerotic plaques: new mechanisms and clinical targets,” Nature Medicine, vol. 8, no. 11, pp. 1257–1262, 2002.
- R. Ross, “Atherosclerosis—an inflammatory disease,” New England Journal of Medicine, vol. 340, no. 2, pp. 115–126, 1999.
- D. Steinberg, “Hypercholesterolemia and inflammation in atherogenesis: two sides of the same coin,” Molecular Nutrition and Food Research, vol. 49, no. 11, pp. 995–998, 2005.
- P. Libby, “Changing concepts of atherogenesis,” Journal of Internal Medicine, vol. 247, no. 3, pp. 349–358, 2000.
- M. R. Bennett, “Apoptosis of vascular smooth muscle cells in vascular remodelling and atherosclerotic plaque rupture,” Cardiovascular Research, vol. 41, no. 2, pp. 361–368, 1999.
- J. J. Boyle, D. E. Bowyer, P. L. Weissberg, and M. R. Bennett, “Human blood-derived macrophages induce apoptosis in human plaque-derived vascular smooth muscle cells by Fas-ligand/Fas interactions,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 21, no. 9, pp. 1402–1407, 2001.
- A. Fernandez-Ortiz, J. J. Badimon, E. Falk et al., “Characterization of the relative thrombogenicity of atherosclerotic plaque components: implications for consequences of plaque rupture,” Journal of the American College of Cardiology, vol. 23, no. 7, pp. 1562–1569, 1994.
- P. Libby, Y. J. Geng, M. Aikawa et al., “Macrophages and atherosclerotic plaque stability,” Current Opinion in Lipidology, vol. 7, no. 5, pp. 330–335, 1996.
- E. Lutgens, E. D. De Muinck, P. J. E. H. M. Kitslaar, J. H. M. Tordoir, H. J. J. Wellens, and M. J. A. P. Daemen, “Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques,” Cardiovascular Research, vol. 41, no. 2, pp. 473–479, 1999.
- A. B. Waqar, T. Koike, Y. Yu et al., “High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits,” Atherosclerosis, vol. 213, no. 1, pp. 148–155, 2010.
- E. Liu, S. Kitajima, Y. Higaki et al., “High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits,” Metabolism, vol. 54, no. 1, pp. 132–138, 2005.
- T. Koike, S. Kitajima, Y. Yu et al., “Human C-reactive protein does not promote atherosclerosis in transgenic rabbits,” Circulation, vol. 120, no. 21, pp. 2088–2094, 2009.
- C. Zhang, H. Zheng, Q. Yu et al., “A practical method for quantifying atherosclerotic lesions in rabbits,” Journal of Comparative Pathology, vol. 142, no. 2-3, pp. 122–128, 2010.
- S. Zhao, C. Zhang, Y. Lin et al., “The effects of rosiglitazone on aortic atherosclerosis of cholesterol-fed rabbits,” Thrombosis Research, vol. 123, no. 2, pp. 281–287, 2008.
- O. Tokunaga, J. Fan, and T. Watanabe, “Atherosclerosis- and age-related multinucleated variant endothelial cells in primary culture from human aorta,” American Journal of Pathology, vol. 135, no. 6, pp. 967–976, 1989.
- P. Cullen, R. Baetta, S. Bellosta et al., “Rupture of the atherosclerotic plaque: does a good animal model exist?” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 23, no. 4, pp. 535–542, 2003.
- P. H. E. Groot, B. J. M. Van Vlijmen, G. M. Benson et al., “Quantitative assessment of aortic atherosclerosis in APOE*3 leiden transgenic mice and its relationship to serum cholesterol exposure,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 16, no. 8, pp. 926–933, 1996.
- H. C. Stary, D. H. Blankenhorn, A. B. Chandler et al., “A definition of the intima of human arteries and of its atherosclerosis-prone regions: a report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association,” Circulation, vol. 85, no. 1, pp. 391–405, 1992.
- P. Libby and P. M. Ridker, “Inflammation and atherosclerosis: role of C-reactive protein in risk assessment,” American Journal of Medicine, vol. 116, no. 6, pp. 9–16, 2004.
- R. Kleemann, L. Verschuren, M. J. Van Erk et al., “Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis,” Genome Biology, vol. 8, no. 9, article R200, 2007.
- Y. V. Bobryshev, “Monocyte recruitment and foam cell formation in atherosclerosis,” Micron, vol. 37, no. 3, pp. 208–222, 2006.
- S. M. Schwartz, D. DeBlois, and E. R. M. O'Brien, “The intima: soil for atherosclerosis and restenosis,” Circulation Research, vol. 77, no. 3, pp. 445–465, 1995.
- H. C. Stary, A. B. Chandler, S. Glagov et al., “A definition of initial, fatty streak, and intermediate lesions of atherosclerosis: a report from the committee on vascular lesions of the council on arteriosclerosis, American Heart Association,” Circulation, vol. 89, no. 5, pp. 2462–2478, 1994.
- H. C. Stary, A. B. Chandler, R. E. Dinsmore et al., “A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: a report from the Committee on Vascular Lesions of the council on arteriosclerosis, American heart association,” Circulation, vol. 92, no. 5, pp. 1355–1374, 1995.
- T. DeVries-Seimon, Y. Li, M. Y. Pin et al., “Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor,” Journal of Cell Biology, vol. 171, no. 1, pp. 61–73, 2005.
- A. Lafont and P. Libby, “The smooth muscle cell: sinner or saint in restenosis and the acute coronary syndromes?” Journal of the American College of Cardiology, vol. 32, no. 1, pp. 283–285, 1998.
- M. Shiomi, T. Ito, Y. Hirouchi, and M. Enomoto, “Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins,” Atherosclerosis, vol. 157, no. 1, pp. 75–84, 2001.
- A. J. Lusis, “Atherosclerosis,” Nature, vol. 407, no. 6801, pp. 233–241, 2000.