Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs
Figure 4
A 3-compartment open model of predicted versus observed drug concentration in the plasma of cefuroxime lysine (a) or cefuroxime sodium (b) under 20 mg/kg of drug administration. The insert showed that the plot of residuals (observed value − predicted) differs at different time points.