Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs

Table 1

Demographic of the drug administrated for 18 beagle dogs.

Antibiotics (mg/kg)^a	Sex^b	Age (m)^c	Weight (kg)^c
			1 week	2 week
20	M	11.3 ± 0.58	13.6 ± 0.40	14.7 ± 0.25
	F	11.0 ± 0	12.9 ± 1.18	13.2 ± 1.22
40	M	10.3 ± 1.15	13.0 ± 1.52	14.0 ± 1.67
	F	12.0 ± 1.73	13.0 ± 2.08	13.6 ± 1.77
80	M	12.3 ± 2.89	11.7 ± 0.35	12.7 ± 0.71
	F	11.0 ± 2.65	10.9 ± 0.64	11.4 ± 0.72

^a: The administrated antibiotics (both cefuroxime forms).
^b: M: male, F: female.
^c: Data are listed as means ± SD, where 𝑛=3.