Table 4: The linear regression equation of cefuroxime lysine and cefuroxime sodium calculated by predicted/observed drug concentrations with a 3-compartment open model.

DoseCefuroxime sodiumCefuroxime lysine
mg/kgRegression equation 𝑅 2 Regression equation 𝑅 2

20 𝑦 = 0 . 9 9 9 8 𝑥 + 0 . 2 1 7 5 0.9885 𝑦 = 0 . 9 6 9 8 𝑥 + 0 . 6 3 9 6 0.9697
40 𝑦 = 0 . 9 7 0 9 𝑥 + 1 . 3 0 3 0.9775 𝑦 = 1 . 0 0 2 𝑥 0 . 1 7 0 7 0.9940
80 𝑦 = 0 . 9 9 1 1 𝑥 + 0 . 6 2 4 4 0.9918 𝑦 = 0 . 9 9 8 6 𝑥 0 . 0 5 8 8 0.9843