Table 4:
The linear regression equation of cefuroxime lysine and cefuroxime sodium calculated by predicted/observed drug concentrations with a 3-compartment open model.
Dose
Cefuroxime sodium
Cefuroxime lysine
mg/kg
Regression equation
𝑅
2
Regression equation
𝑅
2
20
𝑦
=
0
.
9
9
9
8
𝑥
+
0
.
2
1
7
5
0.9885
𝑦
=
0
.
9
6
9
8
𝑥
+
0
.
6
3
9
6
0.9697
40
𝑦
=
0
.
9
7
0
9
𝑥
+
1
.
3
0
3
0.9775
𝑦
=
1
.
0
0
2
𝑥
−
0
.
1
7
0
7
0.9940
80
𝑦
=
0
.
9
9
1
1
𝑥
+
0
.
6
2
4
4
0.9918
𝑦
=
0
.
9
9
8
6
𝑥
−
0
.
0
5
8
8
0.9843