Quantitative Proteomic Study of Human Lung Squamous Carcinoma and Normal Bronchial Epithelial Acquired by Laser Capture Microdissection

Table 4

S100A8 expression in various tissues by IHC.

Classification	Number	—	+	++–+++	P value
Squamous cell carcinomas	30	1	5	24	0.000^a
High differentiated	3	0	0	3	0.705^b
Moderately differentiated	11	2	7	2
Poorly differentiated	10	6	2	2
Normal lung tissue	20	1	11	8
Metastatic carcinoma	29	0	11	18	0.007^c
Other types	20	3	12	5	0.000^d

^a𝑃<0.05 by LSD, squamous cell carcinomas versus normal lung tissue. ^b𝑃>0.05 by ANOVA, high differentiated versus moderately versus poorly. ^c𝑃<0.05 by LSD, metastatic carcinoma versus normal lung tissue. ^d𝑃<0.05 by LSD, other types versus normal lung tissue.