Synthesis of 1,5-Benzodiazepine and Its Derivatives by Condensation Reaction Using H-MCM-22 as Catalyst

Table 1

Effect of weight of H-MCM-22 on the synthesis of 1,5-benzodiazepine.

Weight of catalyst	Reaction time	Yield
mg	Min.	%
50	60	30
100	60	50
150	60	87
200	60	88

Reaction conditions: Substrate: OPDA and acetone, reaction temperature: RT, solvent: acetonitrile.