Review Article

Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging

Figure 10

(a) E9.5: heart tube and doppler spectral trace of ventricular inflow and outflow at 9.5 gestational age. (b) E11.5: doppler spectral trace of ascending aorta outflow at 11.5 gestational age. (c) E12.5: bidimensional image of atrio-ventricular chambers (a–V) interventricular septum (IVS); and doppler spectral trace of ascending aorta outflow at 12.5 gestational age. (d) E13.5: bidimensional image of atrioventricular chambers, interventricular septum, and left ventricle wall (LV wall); doppler spectral trace of ventricular inflow and outflow at 13.5 gestational age. The atrial wave (A-wave) was dominant. The rapid ventricular filling (E-wave) is a measure of ventricular compliance. (e) E15.5: bidimensional image of ventricular chambers, interventricular septum, and left ventricle wall in telesystolic and telediastolic fase of heart cycle in a 15.5 days mouse embryo.
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