Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging

Figure 4

Schematic representation of active targeting of biotin-streptavidine bridges. Streptavidine is used for attachment of biotinylated ligands onto the shell of ultrasound contrast microbubbles. Molecularly targeted microbubbles selective bind to sites of molecular expression on the endothelium.