Review Article

Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging

Figure 9

Multimodality imaging of the lesion: human mammary tumor cells were implanted in the mammary fat pad of an athymic nude mice, 6 weeks old. There is a good correspondence between the morphology and the size of the tumor detected by UBM and necroscopic findings. (a) Bioluminescence of the tumor. (b) 18F-flourothymidine total body PET, tumor uptake is evident (arrow). (c) UBM with measurements of neoplasia. (d) Post mortem dimension of the explanted tumor.
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(a) Bioluminescence
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(b) PET
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(c) UBM
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(d) Necroscopy