Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging
Figure 9
Multimodality imaging of the lesion: human mammary tumor cells were implanted in the mammary fat pad of an athymic nude mice, 6 weeks old. There is a good correspondence between the morphology and the size of the tumor detected by UBM and necroscopic findings. (a) Bioluminescence of the tumor. (b) 18F-flourothymidine total body PET, tumor uptake is evident (arrow). (c) UBM with measurements of neoplasia. (d) Post mortem dimension of the explanted tumor.