Table 6: The effect of carotenoids extracted from dried guajillo pepper on carrageenan-induced paw oedema.

TreatmentDose (mg/kg)Initial paw size (mm)Paw oedema (mm)
1 h3 h5 h

Control03.0 ± 0.11.5 ± 0.11.7 ± 0.11.9 ± 0.8
Indomethacin73.0 ± 0.10.9 ± 0.2a1.1 ± 0.2a0.8 ± 0.2a
Carotenoids extracted
from guajillo pepper
52.9 ± 0.11.1 ± 0.2a1.1 ± 0.1a0.9 ± 0.1a
202.9 ± 0.11.1 ± 0.11.6 ± 0.11.1 ± 0.1a
803.0 ± 0.21.2 ± 0.11.3 ± 0.11.0 ± 0.1a

Results are expressed as mean ± S.E.M ( 𝑛 = 6 ). aStatistical significance with respect to the control treatment was calculated by one-way ANOVA followed by the Dunnett’s test ( 𝑃 0 . 0 5 ). Isotonic saline solution was used as the control and indomethacin was used as the reference treatment.