Table 1: Important surface markers for quantification of human umbilical cord blood content.

Human CD antigensCell types expressed onCD function

CD3T cells, thymocyte subsetWith TCR, TCR surface expression/signal transduction
CD4Thymocyte subset, T subset, monocytes, macrophagesMHC class II coreceptor, HIV receptor, T cell differentiation/activation
CD8Thymocyte subset, T subset, NKMHC class I coreceptor, receptor for some mutated HIV-1, T cell differentiation/activation
CD11cDC, myeloid cells, NK, B, T subsetBinds CD54, fibrinogen, and iC3b
CD17Neutrophils, mono, plateletsLactosylceramide
CD19B, FDCComplex w/CD21 and CD81, BCR coreceptor, B cell activation/differentiation
CD25Tact, Bact, lymph progenitorsIL-2Rα, w/IL-2Rβ, and γ to form high affinity complex
CD34Haematopoietic precursors, capillary endothelial, embryonic fibroblastsStem cell marker, adhesion, CD62L receptor
CD45Haematopoietic cells, multiple isoforms from alternative splicingTyrosine phosphatase, enhanced TCR, and BCR signals
CD56NK, T subset, neurones, some large granular lymphocyte leukemias, myeloid leukemiasAdhesion
CD123Lymph subset, basophils, haematopoietic progenitors, macrophages, DC, megakaryocytesIL-3Rα, w/CDw131
CD133Haematopoietic stem cell subset, epithelial, endothelialAdhesion
7ADDNucleic acid attachmentApoptosis marker and viability assessment
Lin1CD3; T-lymphocytes
CD14; monocytes, macrophages, neutrophils and eosinophils,
CD16; NK-lymphocytes, macrophages, cultured monocytes and neutrophils,
CD19/CD20; B-lymphocytes,
CD56; activated and resting NK-lymphocytes
With TCR, TCR surface expression/signal transduction.
Pattern recognition receptor
Fc receptor
B-cell coreceptor
Adhesion molecule
HLA-DRMacrophages, B-cells and dendritic cellsMHC class II cell surface marker