- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 575471, 15 pages
Amniotic Mesenchymal Stem Cells: A New Source for Hepatocyte-Like Cells and Induction of CFTR Expression by Coculture with Cystic Fibrosis Airway Epithelial Cells
1Medical Genetics Laboratory, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 12, 20122 Milan, Italy
2Department of Biomedical Sciences, University of Foggia, c/o Ospedali Riuniti, Viale L. Pinto 1, 71122 Foggia, Italy
3Interdepartmental Center of Cytometry and Experimental Hepatology Laboratory, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, 20122 Milan, Italy
4Cystic Fibrosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy
Received 15 June 2011; Revised 13 October 2011; Accepted 14 October 2011
Academic Editor: Ken-ichi Isobe
Copyright © 2012 Valentina Paracchini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- T. Miki and S. C. Strom, “Amnion-derived pluripotent/multipotent stem cells,” Stem Cell Reviews, vol. 2, no. 2, pp. 133–142, 2006.
- M. Evangelista, M. Soncini, and O. Parolini, “Placenta-derived stem cells: new hope for cell therapy?” Cytotechnology, vol. 58, no. 1, pp. 33–42, 2008.
- O. Parolini, F. Alviano, G. P. Bagnara et al., “Concise review: isolation and characterization of cells from human term placenta: outcome of the first international workshop on placenta derived stem cells,” Stem Cells, vol. 26, no. 2, pp. 300–311, 2008.
- D. N. Sheppard and M. J. Welsh, “Structure and function of the CFTR chloride channel,” Physiological Reviews, vol. 79, no. 1, supplement, pp. S23–S45, 1999.
- U. Griesenbach and E. W. F. W. Alton, “Cystic fibrosis gene therapy: successes, failures and hopes for the future,” Expert Review of Respiratory Medicine, vol. 3, no. 4, pp. 363–371, 2009.
- M. Conese, E. Copreni, D. Piro, and J. Rejman, “Gene and cell therapy for the treatment of cystic fibrosis,” Advances in Gene, Molecular and Cell Therapy, vol. 1, pp. 99–119, 2007.
- D. Piro, J. Rejman, and M. Conese, “Stem cell therapy for cystic fibrosis: current status and future prospects,” Expert Review of Respiratory Medicine, vol. 2, no. 3, pp. 365–380, 2008.
- R. Loi, T. Beckett, K. K. Goncz, B. T. Suratt, and D. J. Weiss, “Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells,” American Journal of Respiratory and Critical Care Medicine, vol. 173, no. 2, pp. 171–179, 2006.
- E. M. Bruscia, J. E. Price, E.-C. Cheng et al., “Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 8, pp. 2965–2970, 2006.
- V. Sueblinvong, R. Loi, P. L. Eisenhauer et al., “Derivation of lung epithelium from human cord blood-derived mesenchymal stem cells,” American Journal of Respiratory and Critical Care Medicine, vol. 177, no. 7, pp. 701–711, 2008.
- G. Carraro, L. Perin, S. Sedrakyan et al., “Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages,” Stem Cells, vol. 26, no. 11, pp. 2902–2911, 2008.
- T. Miki, F. Marongiu, K. Dorko et al., “Isolation of amniotic mesenchymal stem cells,” Current Protocols in Stem Cell Biology, vol. 1, supplement 12, pp. 1E.3.1–E3.10, 2010.
- F. Marongiu, R. Gramignoli, Q. Sun, et al., “Isolation of amniotic mesenchymal stem cells,” Current Protocols in Stem Cell Biology, vol. 1, supplement 12, pp. 1E.5.1–E.5.11, 2010.
- L. Porretti, A. Cattaneo, F. Colombo et al., “Simultaneous characterization of progenitor cell compartments in adult human liver,” Cytometry A, vol. 77, no. 1, pp. 31–40, 2010.
- T. Miki, F. Marongiu, E. C. Ellis et al., “Production of hepatocyte-like cells from human amnion,” Methods in Molecular Biology, vol. 481, pp. 155–168, 2009.
- K. Anderson, R. Wilkinson, and M. H. Grant, “Assessment of liver function in primary cultures of hepatocytes using diethoxy (5, 6) chloromethylfluorescein and confocal laser scanning microscopy,” International Journal of Artificial Organs, vol. 21, no. 6, pp. 360–364, 1998.
- W. Schormann, F. J. Hammersen, M. Brulport et al., “Tracking of human cells in mice,” Histochemistry and Cell Biology, vol. 130, no. 2, pp. 329–338, 2008.
- D. Piro, C. Piccoli, L. Guerra, et al., “Hematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic fibrosis transmembrane conductance regulator,” Stem Cells and Development. In press.
- L. Guerra, T. Fanelli, M. Favia et al., “Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues ΔF508 CFTR functional expression in cystic fibrosis cells,” Journal of Biological Chemistry, vol. 280, no. 49, pp. 40925–40933, 2005.
- M. F. Pittenger, A. M. Mackay, S. C. Beck et al., “Multilineage potential of adult human mesenchymal stem cells,” Science, vol. 284, no. 5411, pp. 143–147, 1999.
- K. Le Blanc, F. Frassoni, L. Ball et al., “Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study,” The Lancet, vol. 371, no. 9624, pp. 1579–1586, 2008.
- G. D'Ippolito, P. C. Schiller, C. Ricordi, B. A. Roos, and G. A. Howard, “Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow,” Journal of Bone and Mineral Research, vol. 14, no. 7, pp. 1115–1122, 1999.
- R. J. Scheubel, H. Zorn, R. E. Silber et al., “Age-dependent depression in circulating endothefial progenitor cells in patients undergoing coronary artery bypass grafting,” Journal of the American College of Cardiology, vol. 42, no. 12, pp. 2073–2080, 2003.
- C. Heeschen, R. Lehmann, J. Honold et al., “Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease,” Circulation, vol. 109, no. 13, pp. 1615–1622, 2004.
- P. S. In't Anker, S. A. Scherjon, C. Kleijburg-van der Keur et al., “Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta,” Stem Cells, vol. 22, no. 7, pp. 1338–1345, 2004.
- F. Alviano, V. Fossati, C. Marchionni et al., “Term amniotic membrane is a high throughput source for multipotent mesenchymal stem cells with the ability to differentiate into endothelial cells in vitro,” BMC Developmental Biology, vol. 7, article 11, 2007.
- C. B. Portmann-Lanz, A. Schoeberlein, A. Huber et al., “Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration,” American Journal of Obstetrics and Gynecology, vol. 194, no. 3, pp. 664–673, 2006.
- N. Sakuragawa, K. Kakinuma, A. Kikuchi et al., “Human amnion mesenchyme cells express phenotypes of neuroglial progenitor cells,” Journal of Neuroscience Research, vol. 78, no. 2, pp. 208–214, 2004.
- S. Ilancheran, A. Michalska, G. Peh, E. M. Wallace, M. Pera, and U. Manuelpillai, “Stem cells derived from human fetal membranes display multilineage differentiation potential,” Biology of Reproduction, vol. 77, no. 3, pp. 577–588, 2007.
- P. Zhao, H. Ise, M. Hongo, M. Ota, I. Konishi, and T. Nikaido, “Human amniotic mesenchymal cells have some characteristics of cardiomyocytes,” Transplantation, vol. 79, no. 5, pp. 528–535, 2005.
- C. Ventura, S. Cantoni, F. Bianchi et al., “Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts,” Journal of Biological Chemistry, vol. 282, no. 19, pp. 14243–14252, 2007.
- J. P. Wei, T. S. Zhang, S. Kawa et al., “Human amnion-isolated cells normalize blood glucose in streptozotocin-induced diabetic mice,” Cell Transplantation, vol. 12, no. 5, pp. 545–552, 2003.
- R. M. Moore, R. J. Silver, and J. J. Moore, “Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells,” Placenta, vol. 24, no. 2-3, pp. 173–180, 2003.
- M. L. Casey and P. C. MacDonald, “Interstitial collagen synthesis and processing in human amnion: a property of the mesenchymal cells,” Biology of Reproduction, vol. 55, no. 6, pp. 1253–1260, 1996.
- S. Barlow, G. Brooke, K. Chatterjee et al., “Comparison of human placenta- and bone marrow-derived multipotent mesenchymal stem cells,” Stem Cells and Development, vol. 17, no. 6, pp. 1095–1107, 2008.
- S. Wolbank, A. Peterbauer, M. Fahrner et al., “Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue,” Tissue Engineering, vol. 13, no. 6, pp. 1173–1183, 2007.
- T. Tamagawa, S. Oi, I. Ishiwata, H. Ishikawa, and Y. Nakamura, “Differentiation of mesenchymal cells derived from human amniotic membranes into hepatocyte-like cells in vitro,” Human Cell, vol. 20, no. 3, pp. 77–84, 2007.
- G. Bilic, S. M. Zeisberger, A. S. Mallik, R. Zimmermann, and A. H. Zisch, “Comparative characterization of cultured human term amnion epithelial and mesenchymal stromal cells for application in cell therapy,” Cell Transplantation, vol. 17, no. 8, pp. 955–968, 2008.
- M. Bailo, M. Soncini, E. Vertua et al., “Engraftment potential of human amnion and chorion cells derived from term placenta,” Transplantation, vol. 78, no. 10, pp. 1439–1448, 2004.
- M. Soncini, E. Vertua, L. Gibelli et al., “Isolation and characterization of mesenchymal cells from human fetal membranes,” Journal of Tissue Engineering and Regenerative Medicine, vol. 1, no. 4, pp. 296–305, 2007.
- G. Pasquinelli, P. Tazzari, F. Ricci et al., “Ultrastructural characteristics of human mesenchymal stromal (stem) cells derived from bone marrow and term placenta,” Ultrastructural Pathology, vol. 31, no. 1, pp. 23–31, 2007.
- X. R. Tao, W. L. Li, S. Juan et al., “Clonal mesenchymal stem cells derived from human bone marrow can differentiate into hepatocyte-like cells in injured livers of scid mice,” Journal of Cellular Biochemistry, vol. 108, no. 3, pp. 693–704, 2009.
- K. Leelawat, S. Narong, S. Chaijan et al., “Proteomic profiles of mesenchymal stem cells induced by a liver differentiation protocol,” International Journal of Molecular Sciences, vol. 11, no. 12, pp. 4905–4915, 2010.
- S. Kazemnejad, A. Allameh, M. Soleimani et al., “Biochemical and molecular characterization of hepatocyte-like cells derived from human bone marrow mesenchymal stem cells on a novel three-dimensional biocompatible nanofibrous scaffold,” Journal of Gastroenterology and Hepatology, vol. 24, no. 2, pp. 278–287, 2009.
- J. K. Henderson, J. S. Draper, H. S. Baillie et al., “Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens,” Stem Cells, vol. 20, no. 4, pp. 329–337, 2002.
- E. J. Gang, D. Bosnakovski, C. A. Figueiredo, J. W. Visser, and R. C. Perlingeiro, “SSEA-4 identifies mesenchymal stem cells from bone marrow,” Blood, vol. 109, no. 4, pp. 1743–1751, 2007.
- E. Pierantozzi, B. Gava, I. Manini et al., “Pluripotency regulators in human mesenchymal stem cells: expression of NANOG but not of OCT-4 and SOX-2,” Stem Cells and Development, vol. 20, no. 5, pp. 915–923, 2011.
- D. J. Weiss, M. A. Berberich, Z. Borok, et al., “Adult stem cells, lung biology, and lung disease. NHLBI/Cystic fibrosis foundation workshop,” Proceedings of the American Thoracic Society, vol. 3, no. 3, pp. 193–207, 2006.
- G. Wang, B. A. Bunnell, R. G. Painter et al., “Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 1, pp. 186–191, 2005.
- A. Erices, P. Conget, and J. J. Minguell, “Mesenchymal progenitor cells in human umbilical cord blood,” British Journal of Haematology, vol. 109, no. 1, pp. 235–242, 2000.
- K. Mareschi, E. Biasin, W. Piacibello, M. Aglietta, E. Madon, and F. Fagioli, “Isolation of human mesenchymal stem cells: bone marrow versus umbilical cord blood,” Haematologica, vol. 86, no. 10, pp. 1099–1100, 2001.
- S. A. Wexler, C. Donaldson, P. Denning-Kendall, C. Rice, B. Bradley, and J. M. Hows, “Adult bone marrow is a rich source of human mesenchymal “stem” cells but umbilical cord and mobilized adult blood are not,” British Journal of Haematology, vol. 121, no. 2, pp. 368–374, 2003.
- A. Ben-Chetrit, M. Antenos, A. Jurisicova et al., “Expression of cystic fibrosis transmembrane conductance regulator during early human embryo development,” Molecular Human Reproduction, vol. 8, no. 8, pp. 758–764, 2002.
- X. T. Mo, S. C. Guo, H. Q. Xie et al., “Variations in the ratios of co-cultured mesenchymal stem cells and chondrocytes regulate the expression of cartilaginous and osseous phenotype in alginate constructs,” Bone, vol. 45, no. 1, pp. 42–51, 2009.
- L. Bian, D. Y. Zhai, R. L. Mauck, and J. A. Burdick, “Coculture of human mesenchymal stem cells and articular chondrocytes reduces hypertrophy and enhances functional properties of engineered cartilage,” Tissue Engineering A, vol. 17, no. 7-8, pp. 1137–1145, 2011.
- Y. Maeda, V. Dave, and J. A. Whitsett, “Transcriptional control of lung morphogenesis,” Physiological Reviews, vol. 87, no. 1, pp. 219–244, 2007.
- L. Badri, N. M. Walker, T. Ohtsuka et al., “Epithelial interactions and local engraftment of lung-resident mesenchymal stem cells,” American Journal of Respiratory Cell and Molecular Biology, vol. 45, no. 4, pp. 809–816, 2011.
- T. S. Jiang, L. Cai, W. Y. Ji et al., “Reconstruction of the corneal epithelium with induced marrow mesenchymal stem cells in rats,” Molecular Vision, vol. 16, pp. 1304–1316, 2010.
- J. Xu, X. Liu, J. Chen et al., “Cell-cell interaction promotes rat marrow stromal cell differentiation into endothelial cell via activation of TACE/TNF-α signaling,” Cell Transplantation, vol. 19, no. 1, pp. 43–53, 2010.
- S. L. Farmen, P. H. Karp, P. Ng et al., “Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR,” American Journal of Physiology, vol. 289, no. 6, pp. L1123–L1130, 2005.
- C. Colombo, “Liver disease in cystic fibrosis,” Current Opinion in Pulmonary Medicine, vol. 13, no. 6, pp. 529–536, 2007.
- K. Moyer and W. Balistreri, “Hepatobiliary disease in patients with cystic fibrosis,” Current Opinion in Gastroenterology, vol. 25, no. 3, pp. 272–278, 2009.