Research Article

Physical Properties and Biocompatibility of a Core-Sheath Structure Composite Scaffold for Bone Tissue Engineering In Vitro

Figure 3

(a) Morphological observation of BMSCs cultured on the core-sheath structure composite scaffold by SEM after 4 hours (×3.0 k). Note: the arrows point to the BMSCs adhered on the scaffold and the pseudopodium of the cells. (c and d) Morphological observation of BMSCs cultured on the core-sheath structure composite scaffold by SEM after 2 days (×500,1000). Note: the arrows point to the BMSCs stretched onto the scaffold. (g and h) Morphological observation of BMSCs cultured on the core-sheath structure composite scaffold by SEM after 6 days (×300,1000). Note: the arrows point to the BMSCs. (k, l, m, and n) Morphological observation of BMSCs cultured on the core-sheath structure composite scaffold by SEM after 14 days (×500,1000). Note: (k and l) the arrows point to the BMSCs and secreted ECM by BMSCs. (m and n) the arrows point to the BMSCs growed into the holes of the scaffold. (b) Morphological observation of BMSCs cultured on the PLGA/β-TCP skeleton after 4 hours (×3.0 k). (e and f) Morphological observation of BMSCs cultured on the PLGA/β-TCP skeleton after 2 days (×500,1000). Note: the arrows point to the BMSCs. (I and j) Morphological observation of BMSCs cultured on the PLGA/β-TCP skeleton after 6 days (×500,1000). Note: the arrows point to the BMSCs. (o and p) Morphological observation of BMSCs cultured on the PLGA/β-TCP skeleton after 14 days (×400,1000). Note: the arrows point to the BMSCs.
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