A Novel Antihepatitis Drug, Bicyclol, Prevents Liver Carcinogenesis in Diethylnitrosamine-Initiated and Phenobarbital-Promoted Mice Tumor Model

Figure 2

Gross liver tumor and nodule phenotypes in DEN/PB-induced ICR mice and the preventive effect of bicyclol at week 20. (a) Photographs of representative livers. (b) Determination of liver tumor and number of nodules per liver greater than approximately 1 mm in diameter. Average values with standard deviations are shown. 𝑛=8–10. ^##𝑃<0.01 compared with the control group; *𝑃<0.01, **𝑃<0.01 compared with the DEN/PB model group.

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(b)