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Figure 4: Histological study of the liver tissue obtained from the control and experimental groups at week 20. H&E-stained liver sections were photographed at 100x magnification. Insets in the bottom-left corners are images at 20x magnification of the liver tissue from which the 100x photographs were taken. Control group animals revealed normal architecture. DEN/PB-induced animals showed loss of architecture and presence of cancer cells. Animals pretreated with bicyclol (100, 200 mg/kg) showed fewer neoplastic cells and near-normal architecture.