Research Article

Structural Insights into Interaction between Mammalian Methionine Sulfoxide Reductase B1 and Thioredoxin

Table 1

Structural parameters for MsrB1-Trx complexes (four groups) revealed by protein docking. The distances between sulphur atom of Cys32 of Trx and the nearest sulphur atom of MsrB1 disulfide bond as well as three pairs of the nearest aminoacids approaching in space for each group (to outline the spatial orientation of the proteins within a complex) are presented.

Group AGroup BGroup CGroup D

Distance, Å (Trx Cys32) S/S–S bond (MsrB1)7,17,87,85,3

Nearest neighbouring contacts between residues

MsrB1 residuesW43H39P87S2W43P87W43N62P87F6P42R93
Trx residuesM37E95S90W31 A92E70 M37K72K96K72D60K36