Table 2: Effect of cranberry NDM on preformed S. gordonii biofilm.

NDM concentration (μg/mL)Metabolic activityBiofilm mass

0 (control) 2 . 2 1 ± 0 . 3 2 . 3 6 ± 0 . 4 1
2.5 2 . 1 4 ± 0 . 1 8 2 . 3 3 ± 0 . 3 3
5.0 2 . 2 4 ± 0 . 2 2 2 . 3 9 ± 0 . 2 7
7.5 2 . 0 6 ± 0 . 4 2 . 3 5 ± 0 . 4 4
10 1 . 9 6 ± 0 . 3 3 2 . 4 1 ± 0 . 3 1
20 1 . 8 4 ± 0 . 5 9 2 . 3 4 ± 0 . 4 1
25 1 . 9 7 ± 1 . 1 2 . 3 6 ± 0 . 2 9
50 1 . 8 6 ± 0 . 6 9 2 . 3 9 ± 0 . 3
100 1 . 0 8 ± 0 . 4 4 2 . 3 5 ± 0 . 2 8

Bacterial biofilm prepared as described previously was treated with varying concentrations of NDM (2.5 μg/mL to 100 μg/mL) for 60 minutes and 4 hours. The metabolic activity was determined by XTT assay and the biofilm mass determined by the crystal violet staining.