Table 1: Frequency of IRF5 haplotypes in lupus patients and healthy controls. Haplotype frequencies observed in controls and systemic lupus erythematosus (SLE) patient cohort at single-nucleotide polymorphisms rs2004640 (T : risk, G: protective) and rs10954213 (A: risk, G: protective).

HaplotypeAllele 1Allele 2Frequency (patients) 𝑛 = 1 3 9 0 Frequency (controls) 𝑛 = 2 0 3 9 SLE risk

1TATA0.25760.1947Risk/risk
2TATG0.4460<0.0001Risk/neutral
3GAGG0.21080.2737Protective/protective
4GGTG0.01650.1810Protective/neutral