Research Article
The Effect of Bradykinin B2 Receptor Polymorphisms on the Susceptibility and Severity of Osteoarthritis in a Chinese Cohort
Table 2
The genotype distributions and allele frequencies of BDKRB2 polymorphisms in knee OA and control subjects.
| | | OA |
% | Control |
% | OR | 95% CI | | |
| +9/−9 | +9/+9 | 44 | 17.96% | 67 | 25.38% | 1 | | | | | +9/−9 | 119 | 48.57% | 144 | 54.55% | 1.258 | 0.801 | 1.976 | 0.998 | 0.318 | −9/−9 | 82 | 33.47% | 53 | 20.08% | 2.356 | 1.409 | 3.938 | 10.856 | <0.001 | +9 | 207 | 42.24% | 278 | 52.65% | 1.000 | | | | | −9 | 283 | 57.76% | 250 | 47.35% | 1.520 | 1.187 | 1.947 | 11.034 | <0.001 |
| | TT | 80 | 32.65% | 64 | 24.24% | 1.000 | | | | | TC | 102 | 41.63% | 121 | 45.83% | 0.674 | 0.443 | 1.028 | 3.372 | 0.066 | CC | 63 | 25.71% | 79 | 29.92% | 0.638 | 0.400 | 1.017 | 3.581 | 0.058 | T | 262 | 53.47% | 249 | 47.16% | 1.000 | | | | | C | 228 | 46.53% | 279 | 52.84% | 0.777 | 0.607 | 0.994 | 4.048 | 0.044 |
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