Research Article

Triiodothyronine Represses MUC5AC Expression by Antagonizing Sp1 Binding to Its Promoter in Human Bronchial Epithelial HBE16 Cells

Figure 1

T3 inhibits MUC5AC mRNA expression and protein secretion in HBE16 cells. (a) MUC5AC mRNA level was determined by RT-PCR. (b) Secreted MUC5AC protein level was determined by ELISA. 𝑃 < 0 . 0 5 versus control group; # 𝑃 > 0 . 0 5 versus 10 nM group.
648170.fig.001a
(a)
648170.fig.001b
(b)